Edo G has released four solo albums and two EPs, toured around the world, and worked with other artists including Pete Rock, DJ Premier, RZA, KRS-One, Common, Black Thought of the Roots, and Masta Ace.

On his solo album The Truth Hurts, he combined with DJ Premier and Pete Rock; "Wishful Thinking" was a sequel of his first solo performance. The connection with Rock turned into a partnership for the album My Own Worst Enemy. One of the album's songs, "Wishing" (featuring Masta Ace), was featured on The Boondocks in episode 9, Return of the King.

In 2005, Edo G started a new group called Special Teamz with fellow Boston rappers Jaysaun (of Kreators) and Slaine (of La Coka Nostra). They released a mixtape on November 11, 2005 entitled The Mixtape. Special Teamz released the album, Stereotypez, on September 25, 2007, which featured production from Pete Rock, DJ Premier, and specialist producer Marco Polo, who had previously collaborated with Jake One and Ill Bill. Appearances on the album included Buckshot and Sean Price of the Boot Camp Click, Ill Bill, Akrobtik, and Devin the Dude.

Edo G proceeded to work on a new album with Masta Ace. The first single, titled "Little Young" was released via Myspace. The album was scheduled for release in October 2009, but the release was delayed by a cease-and-desist order from A&E Television Networks, which required a complete revision of the album cover artwork and design[why?].

Edo G is also a member of the Boston hip hop group 4Peace along with Twice Thou, Wyatt Jackson, and DQuest.